tert-Butyl [(2R)-morpholin-2-ylmethyl]carbamate

tert-Butyl [(2R)-morpholin-2-ylmethyl]carbamate - Names and Identifiers

Name	(R)-2-N-Boc-aminomethylmorpholine
Synonyms	(R)-2-N-Boc-aminomethylmorpholine (R)-2-(Boc-aMinoMethyl)Morpholine (R)-tert-Butyl (Morpholin-2-ylMethyl)carbaMate tert-Butyl-[(2R)-morpholin-2-ylmethyl]carbamat tert-Butyl [(2R)-morpholin-2-ylmethyl]carbamate tert-butyl N-[(2R)-morpholin-2-ylmethyl]carbamate 1,1-Dimethylethyl [(2R)-2-morpholinylmethyl]carbamate Carbamic acid, N-[(2R)-2-morpholinylmethyl]-, 1,1-dimethylethyl ester carbamic acid, N-[(2R)-2-morpholinylmethyl]-, 1,1-dimethylethyl ester
CAS	186202-57-3
InChI	InChI=1/C10H20N2O3/c1-10(2,3)15-9(13)12-7-8-6-11-4-5-14-8/h8,11H,4-7H2,1-3H3,(H,12,13)/t8-/m1/s1

tert-Butyl [(2R)-morpholin-2-ylmethyl]carbamate - Physico-chemical Properties

Molecular Formula	C10H20N2O3
Molar Mass	216.28
Density	1.032±0.06 g/cm3(Predicted)
Boling Point	334.0±17.0 °C(Predicted)
Flash Point	155.8°C
Vapor Presure	0.000131mmHg at 25°C
pKa	12.22±0.46(Predicted)
Storage Condition	2-8°C
Refractive Index	1.452
Physical and Chemical Properties

tert-Butyl [(2R)-morpholin-2-ylmethyl]carbamate - Introduction

(R)-is an organic compound. It is a colorless liquid with a special aminomethyl and methyl protecting group (Boc) structure. The chemical properties of this compound are very stable.

(R)-has a wide range of applications in organic synthesis. It can be used as a chiral reagent to catalyze asymmetric reactions, such as asymmetric hydrogenation, asymmetric nucleophilic substitution, asymmetric induced radical substitution, etc. It can also be used as an important intermediate in the synthesis of drugs. Due to its chiral properties, it also has an effect on the stereoconfiguration of the drug molecule.

The method of preparing (R)-is to react (R)-2-aminomethylmorpholine with N-tert-butoxycarbonyl anhydride (Boc-OSu) under alkaline conditions, the target product is generated.

Regarding safety information, first of all, this compound should be handled under safe ventilation and avoid inhalation or contact with skin and eyes. Secondly, contact with strong oxidizing agents should be avoided, which could lead to dangerous reactions. Disposal of used chemicals and waste shall be in strict compliance with local laws and regulations.

Last Update：2024-04-09 21:01:54